The nanny state is about trying to tell people how to live their lives. What I'm talking about let's people make their own choices, provides people with information to help them make choices, and addresses legitimate public safety concerns from some of the drugs that can pose some threat to public safety when the person doesn't know what they are doing. Take, PCP or methamphetamine for example. LSD was probably a bad example since violence or aggression or harm to self or others on LSD is rare but there have been cases. A few cases is not cause to ban something. PCP or methamphetamine on the other hand should be done only in supervision, this provides users a safer way. Keeping them illegal just means people do them anyways in more dangerous settings.
Some like "Datura" which aren't even illegal now should be controlled in a similar manner as I described for these most harmful drugs. Datura is a plant containing scopolamine which can be used to render a subject into a delirium where they are completely obedient. If someone wants to experience that it should only be done in a carefully regulated supervised setting, in fact in this case to guarantee it isn't abused by the operators of these facilities there would need to be more oversight.